cannabis tolerance reset

How to do a Cannabis Tolerance Reset

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by Dan Larkin.

Do you know how to do a cannabis tolerance reset? Do you need a cannabis tolerance reset? What the heck is a cannabis tolerance reset?

All really good questions. Let’s see if I can answer them for you. Let’s go in reverse order. First up:

What’s a cannabis tolerance reset?

If you’ve consumed cannabis for a long time you may find that it takes more of it to achieve your desired effect than it did the first time you tried it. That’s pretty normal. But, it also may signal that it’s time for a cannabis tolerance reset. That means you may need to take a break from cannabis for a period of time in order to reset your body’s endocannabinoid receptors.

How long does it take to reset your cannabis tolerance level? Well, I will get into that in a second. But, first let’s answer question two:

Do you need a cannabis tolerance reset?

Do you remember the first time you tried cannabis? Hopefully, it was a good experience. It probably only took a small amount to get you to where you wanted to go. Whether your goal was to get elevated, to relax, to alleviate pain, or whatever, it did the trick, right?

Well, as time went by (and this is subjective because everyone is affected differently) you may have chosen to incorporate regular cannabis use into your life. It might be a daily thing. Maybe even throughout the day for some. (Again, everyone’s tolerance is different.) Whatever the case, if you are a regular cannabis consumer you may have noticed that it takes a little more of it to get to where you want to be. Again, that’s natural. Here’s why. Oh, and sorry, but this part is a little “science-y”.

The endocannabinoid system and your CB1 &2 receptors.

You see, your body has an endocannabinoid system that helps you maintain your health or homeostasis. In other words, it helps regulate your body and provide balance. Cannabinoids found in cannabis work with your CB1 receptors within the endocannabinoid system. The CB1 receptors are activated to go to work by cannabinoids (such as THC or CBD) to heal or calm you. Over time, these CB1 receptors can get worn out and become less sensitive. Then, they eventually die.

But don’t worry, new ones are created by your body all the time. It’s just that frequent cannabis use can sometimes mean your endocannabinoid system needs a timeout. That way it can catch-up and provide your “normal” desired effect.

So, if you’re noticing it’s taking an extra gummy, a few more puffs, or maybe more drops out of the tincture bottle than you used to take, you probably need a cannabis tolerance reset. But how do you do that? Here’s how:

How to do a cannabis tolerance reset.

The bottom line here is that you need to abstain from using cannabis for a length of time. Now, please keep in mind that I am not a doctor, nor do I offer any medical advice. So, if you are under a doctor’s care and cannabis is part of your treatment, please consult them before making any changes.

Having said that, here’s what you need to do. If you want a full reset of your CB1 receptors, you should eliminate cannabis use for 4 weeks. That will give your body plenty of time to replace all of your lost CB1 receptors.

You can actually start replacing those receptors by stopping for as little as two days. For many people, even abstaining for as little as 48 hours provides a noticeable difference. That’s great. But, if you abstain for a longer period of time you should be able to go longer without needing another reset.

Two weeks seems to be a popular length of time for daily or even more frequent cannabis consumers. With that length of time, you won’t get back to your original or baseline level of tolerance, but it will provide a real noticeable difference.

Once you’re done with your reset, start back with microdosing. Take a much smaller amount than usual and then wait to feel the effect. If necessary try another microdose and again wait to see if it’s doing the job for you. It’s almost certain you’ll be happily surprised!


Cannabis has so many wonderful things to offer. It provides enjoyment, health, pain relief, relaxation, and quality of life. Our bodies know how to utilize it to provide us with what we need from it. You can help by monitoring how it’s working for you and, if necessary, take a cannabis tolerance break to help maximize your experience.

Again, always consult your health professional before making any radical changes to your health regime. Enjoy your cannabis and be well!

Read more CannabisIRL articles about the endocannabinoid system here.

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